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<b>How does ursodiol help the liver?</b> Ursodiol is a naturally-occurring bile acid that is made by the liver in humans and is secreted in small quantities into bile. It is used to dissolve and prevent cholesterol gallstones and to treat primary biliary cirrhosis, a disease of the liver. It also reduces the absorption of cholesterol from the intestine.
<b>What is the life expectancy of someone with PBC?</b> Advances in treatment have extended the life expectancy in the past many years. The average survival from diagnosis for a patient with PBC who is asymptomatic is 16 years, while that of patients with symptoms is 7 1/2 years.
<b>Do you poop out gallstones?</b> The good news is you can pass small gallstones. Dr. McKenzie says some small gallstones leave your gallbladder and pass into your bile ducts. The stones that don’t get stuck move into the small bowel and are passed in your stool. However, the stones that get stuck are the ones that cause problems.
<b>What are the four stages of PBC?</b> Liver biopsy also helps stage PBC, which has 4 histologic stages: Stage 1: Inflammation, abnormal connective tissue, or both, confined to the portal areas. Stage 2: Inflammation, fibrosis, or both, confined to the portal and periportal areas. Stage 3: Bridging fibrosis. Stage 4: Cirrhosis.
<b>How long can you live after being diagnosed with cirrhosis of the liver?</b> Cancer: People often develop liver cancer before they develop cirrhosis. You may die within 3-6 months after diagnosis if the cancer remains untreated. Even with treatment, people rarely survive beyond 5 years.
<b>What is treatment for PBC?</b> Medications used to treat PBC itself include most commonly ursodeoxycholic acid (UDCA), rarely colchicine (Colcrys), and sometimes certain immunosuppressive medications, such as corticosteroids. The UDCA is the most effective and safe treatment.
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